Interferon γ in patients with HIV/AIDS and suspicion or latent tuberculosis infection
Asian Pacific Journal of Tropical Medicine
;
(12): 135-138, 2013.
Article
in English
| WPRIM
| ID: wpr-820554
ABSTRACT
OBJECTIVE@#To assess the usefulness of IGRA test (QuantiFERON(®)-Cell mediated immune) compared with the tuberculin skin test.@*METHODS@#A cross-sectional study was carried out in Mexico, 25 infected patients with HIV-AIDS and the suspicion or with latent tuberculous infection (LTBI) who were >18 years of age and without treatment for tuberculosis (TB), were enrolled in the study.@*RESULTS@#Median cluster of differentiation (CD4) count was 364 cells/μ L and median HIV viral load was 50 copies/mL. Overall, 20 patients (80%) had at least one positive diagnostic test for LTBI four (16%) had a positive tuberculin skin test and 19 (76%), a positive QuantiFERON(®)-tuberculosis.@*CONCLUSIONS@#No agreement is found between the two diagnostic tests k = -0.004, 95% confidence interval (-0.2219, 0.2210). Additional longitudinal studies among HIV-infected populations with high prevalence of TB are needed to further assess the usefulness of IGRAs in this patient population.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Virology
/
Tuberculin Test
/
HIV Infections
/
Cross-Sectional Studies
/
Interferon-gamma
/
Statistics, Nonparametric
/
CD4 Lymphocyte Count
/
Viral Load
/
Diagnosis
/
Allergy and Immunology
Type of study:
Diagnostic study
/
Observational study
/
Prevalence study
/
Risk factors
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
Language:
English
Journal:
Asian Pacific Journal of Tropical Medicine
Year:
2013
Type:
Article
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