Free radical scavenging potential of Lagenaria siceraria (Molina) Standl fruits extract
Asian Pacific Journal of Tropical Medicine
;
(12): 20-26, 2013.
Article
in English
| WPRIM
| ID: wpr-820573
ABSTRACT
OBJECTIVE@#To elucidate free radical scavenging activity of ethanolic extract Lagenaria siceraria (L. siceraria) (Molina) fruit.@*METHODS@#The free radical scavenging activity of the L. siceraria (Molina) fruit extract was assayed by using α,α-diphenyl-β-picrylhydrazyl (DPPH), 2,20-azinobis 3-ethyl benzothiazoline-6-sulfonate (ABTS), FRAP, reducing power, chelating ability and β-carotene bleaching assay.@*RESULTS@#The IC(50) values of DPPH and ABTS radical-scavenging activity was found to be 1.95 mg/mL and 19 mg/mL, respectively. In ferrous chelation assay, the percentage of inhibition was found to be 89.21%. The reducing power of ethanolic extract of L. siceraria (Molina) fruit was 0.068 at 1 mg/mL and increased to 0.192 at 5 mg/mL. The β-carotene linoleate bleaching assay was 46.7% at 5 mg/mL and antioxidant activity using FRAP at 0.305 for 1 mg/mL to 0.969 for 5 mg/mL.@*CONCLUSIONS@#The results indicate that L. siceraria (Molina) fruit could be an important sources of natural radical scavengers.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Oxidation-Reduction
/
Pharmacology
/
Picrates
/
Sulfonic Acids
/
Thiazoles
/
Biphenyl Compounds
/
Plant Extracts
/
Chemistry
/
Iron Chelating Agents
/
Beta Carotene
Language:
English
Journal:
Asian Pacific Journal of Tropical Medicine
Year:
2013
Type:
Article
Similar
MEDLINE
...
LILACS
LIS