Downstaging conversion therapy for advanced primary liver cancer / 临床肝胆病杂志

ABSTRACT

Most patients with primary liver cancer in China are in the advanced stage at initial diagnosis and lose the opportunity for surgical treatment, and therefore, how to reduce advanced liver cancer to resectable liver cancer is a hot topic in clinical research in recent years. The key premise of successful conversion is to screen out the individuals who are suitable for conversion or may achieve successful conversion through comprehensive examination and necessary multidisciplinary consultation. This article introduces the conversion strategy and the antitumor strategy for liver cancer with lung metastasis, portal vein tumor thrombus, massive tumor dissemination, or multiple tumors, liver cancer with liver function decompensation, liver cancer with liver cancer dissemination and metastasis and an ECOG constitution score of ＞2, and liver cancer with a high HBV load, which has certain guiding significance in the downstaging conversion therapy for advanced liver cancer in clinical practice.