Analysis of clinical characteristics and drug resistance of 57 patients with Salmonella infection / 公共卫生与预防医学

ABSTRACT

Objective To analyze the clinical characteristics and drug resistance of 57 patients with Salmonella infection, and to understand the sensitivity of Salmonella to commonly used antibiotics. Methods Clinical data of 57 Salmonella infection patients admitted in our hospital from January 2016 to February 2019 were collected. After hospitalization, routine examinations such as hematuria and stool were carried out, and fecal bacterial culture and drug sensitivity tests were performed. Results Among the 57 patients, the highest incidence of clinical symptoms was abdominal pain and diarrhea (57 cases, 100%), with an average of 7.46±2.03 times. The others were nausea and vomiting (45 cases, 78.95%), fever (43 cases, 75.44%), headache (34 cases, 59.65%), tenesmus (26 cases, 45.61%) and dehydration (25 cases, 43.86%). The results of stool routine examination showed that 51 cases (89.47%) were positive for fecal leukocytes and 45 cases (78.95%) were positive for fecal occult blood test. The results of urine routine test showed that 45 cases (78.95%) were positive for proteinuria and 38 cases (66.67%) for occult blood test. The results of blood routine examination showed that the average value of leukocyte count was (9.98±4.22)×109/L, neutrophils accounted for 79%, and C-reactive protein was (60.15±32.48)mg/L. The results of drug sensitivity showed that the resistant strains to cephalosporins and quinolones accounted for a large proportion of the total strains. Conclusion The main symptoms of Salmonella infection in this area were abdominal pain and diarrhea. Fecal examination and routine urine examination were more valuable for diagnosis. The detection of resistance to quinolone and cephalosporin antibiotics should be strengthened to provide a basis for rational use of drugs.