Effect of Succinylcholine on the Intra-ocular Pressure / 대한마취과학회지

ABSTRACT

Effect of succinyleholine on the intra-ocular pressure was assessed in 29 surgical patients. After pretreatment of thiopental in a dose to induce the loss of eye-lid reflex the intra- ocular pressure was measured following intravenous administrdtion of succinylcholine. The following were the results. 1) Thiopental showed a significant lowering effect on the intra-ocular pressure. 2) A small dose(0.5mg/kg) of succinylcholine, given immediately after thiopental restored the intra-ocular pressure to the preanesthetic level. 3) A large dose(1.0~2.0mg/kg) of succinylcholine, administered immediately after thiopental, sustained the intra-ocular pressure below the preanesthetic leve. 4) Teacheal intubation caused a rise of the intra-ocular pressure above the preanesthetic level, more significantly than that of succinyleholine. 5) Suecinylcholine, in a large dose, showed a depressing effect on elevation of the intraocular pressure induced by tracheal intubation.