Application of CDK4 / 6 inhibitors in the treatment of hormone receptor-positive breast cancer / 国际肿瘤学杂志
Journal of International Oncology
;
(12): 617-619, 2019.
Article
in Chinese
| WPRIM
| ID: wpr-823566
ABSTRACT
With roles of blocking cell proliferation,cyclin-dependent protein kinase (CDK)4 / 6 inhi-bitors are effective and safe complementary therapies for hormone receptor-positive breast cancer. CDK4 / 6 inhibitors combined with endocrine therapy significantly improve the prognosis of patients with advanced or metastatic breast cancer,especially those with endocrine resistance. Indications for CDK4 / 6 inhibitors are also expected to broaden into early-stage breast cancer. However,mechanisms of resistance of CDK4 / 6 inhibitors remain elusive.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of International Oncology
Year:
2019
Type:
Article
Similar
MEDLINE
...
LILACS
LIS