Application effect of exercise rehabilitation therapy on patients with chronic heart failure / 心血管康复医学杂志

ABSTRACT

To explore influence of exercise rehabilitation therapy on inflammatory factor levels and cardiac func‐tion in patients with chronic heart disease (CHD).Methods:A total of 92 CHF patients of our department from Jun 2016 to May 2018 were randomly and equally divided into routine treatment group and exercise rehabilitation group (received ex‐ercise rehabilitation training based on routine treatment group ) ,both groups were intervened for six months .Cardiac func‐tion ,6min walking distance (6MWD) ,levels of inflammatory factors ,quality of life (QOL) before and after treatment were observed and compared between two groups .Results:Compared with routine treatment group after six months ,there were significant reductions in left ventricular end diastolic volume [LVEDV ,(61.26 ± 8.03) ml vs.(55.77 ± 7.75) ml] , left ventricular end systolic volume [LVESV ,(54.89 ± 6.15) ml vs.(51.36 ± 4.99) ml] ,levels of CRP [(21.41 ± 4.14) ng／ml vs.(18.18 ± 4.22) ng／ml] ,TNF‐α [ (18.46 ± 4.69) ng／ml vs.(15.67 ± 3.37) ng／ml] ,IL‐6 [ (80.09 ± 14.47) ng／ml vs.(71.88 ± 16.16) ng／ml] ,score of Minnesota living with heart failure questionnaire [ (49.50 ± 6.91) scores vs. (46.74 ± 5.12) scores] ,and significant rise in LVEF [ (43.11 ± 4.59)% vs.(45.33 ± 5.58)%] and 6MWD [ (265.70 ± 12.37) m vs.(336.89 ± 11.23) m] in exercise rehabilitation group , P＜0.05 or ＜0.01. Conclusion:Exercise rehabilita‐tion therapy can significantly improve inflammatory factor levels ,cardiac function and QOL ,and reduce rehospitalization rate within six months in CHF patients .