Event-related potential characteristics analysis on vigilant attention development of school-age children / 中华行为医学与脑科学杂志

ABSTRACT

Objective To explore the characteristics of event-related potential(ERP) in the development of alert attention of children aged 6-11 years old.Methods A total of 144 children aged 6-11 years old were enrolled in a continuous performance test (CPT,Go/Nogo stimulus task).The latency and amplitude of frontal region cue/uncue-P3 and CNV were analyzed and compared in all age groups.Results (1)Behavioral comparison among different age groupscorrect number(35 (31,38),37 (34,38.25),37 (34.75,39),38(35,39.25),39(37.25,40),39(39,40)),correct reaction time ((566.88± 86.63) ms,(530.10±83.40) ms,(509.17±88.99)ms,(488.31±76.23)ms,(463.45±75.78)ms,(417.24±75..78)ms),the differences were statistically significant (P＜ 0.01).(2) Fz lead ERP characteristics①Comparison of cueCNV and uncue-CNV6-year-old group((-8.54±4.56) μV vs (-10.13±6.36) μV),7-year-old group ((-9.20±5.34) μV vs (-11.53±4.29) μV),8-year-old group((-8.37±4.78) μV vs (-11.35±6.38) μV) in amplitude and 9-year-old group((689.25±268.22) ms vs (826.13± 174.62) ms) in latency were significantly different (P＜0.05).(②)Comparison of cue-P3 and uncue-P36-year-old group((4.29±4.11) μV vs (7.45±3.83) μV),7-year-old group((4.47±4.71) μV vs (5.82±4.40) μV),8-year-old group((3.76± 3.39) μV vs (6.24 ± 4.91) μV),9-year-old group ((4.27 ± 3.57) μV vs (5.93 ± 3.08) μV),11-year-old group ((4.24±4.66) μV vs (6.13 ±4.42) μV) in amplitude were significantly different (P＜ 0.05).③Longitudinal comparison among age groupsthe latency of cue-CNV in 9-year-old group and 11-year-old group were shorter,and the difference was significant(P＜0.05).The amplitudes of cue-CNV and cue-P3 in 10-year-old group were shorter than those in other age groups(P＜0.05).Conclusion With the increase of age,the reaction time of school-age children shortened and the correct rate improved.The age of 9-10 may be the highspeed period of the development for brain network on vigilant attention and psychological prediction which may be related to the maturation and development of frontal cortex.