Clinical features and prognosis of extrahepatic biliary neuroendocrine neoplasms / 中华普通外科杂志
Chinese Journal of General Surgery
;
(12): 964-967, 2019.
Article
in Chinese
| WPRIM
| ID: wpr-824744
ABSTRACT
Objective To investigate the clinical features and prognostic factors of extrahepatic biliary neuroendocrine neoplasms(EB-NENs).Methods The clinical data and survival of 21 patients with EB-NENs admitted from May 2014 to May 2018 were analyzed retrospectively.Results These 21 EB-NENs patients accounted for 1.6% (21/1313) of all biliary tract neoplasms treated during the study period.Seven (33.3%) cases had lymph node metastasis.Five (23.8%) suffered from distant metastasis.The follow up time was (4 ~ 46.5) months with median survival time of (23.23 ± 4.17) months.Univariate analysis showed that the risk factors for survival were tumor TNM stage (x2 =9.066,P =0.003),lymph node metastasis(x2 =6.399,P=0.011) and distant metastasis (x2 =9.808,P=0.002).By multivariate analysis,independent risk factors were tumor TNM stage (P =0.008,RR =3.003,95% CI1.332 ~ 6.774),lyraph node metastasis (P =0.023,RR =5.382,95 % CI1.261 ~ 22.971) and distant metastasis or not(P =0.007,RR =7.423,95% CI1.730 ~ 31.851).Conclusion EB-NENs was a rare malignant tumor with poor prognosis.Tumor TNM stage,lymph node metastasis and distant metastasis were independent prognostic factors for EB-NENs patients.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Prognostic study
/
Risk factors
Language:
Chinese
Journal:
Chinese Journal of General Surgery
Year:
2019
Type:
Article
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