Recent advances of molecular biology technology in Chlamydia trachomatis detection / 中华检验医学杂志

ABSTRACT

Chlamydia trachomatis (CT) is a prevalent pathogen clinically causing trachoma and sexually transmitted diseases. This review presents the progress and application of molecular biology techniques in CT detection according to different types of methodologies, mainly including real-time PCR amplification tests, nucleic acid isothermal amplification tests, PCR-hybridization, sequence analysis and compare their advantages and disadvantages. The recent developments of the point-of-care testing for CT are also briefly introduced in this paper.