Anti-tumor Activity and Survival Impact of Whole Adlay Hot Water Extract in Sarcoma Mouse Model / 日本補完代替医療学会誌
Japanese Journal of Complementary and Alternative Medicine
;
: 37-42, 2020.
Article
in English
| WPRIM
| ID: wpr-826210
ABSTRACT
Background:
Adlay (Coix lacryma-jobi L. var. ma-yuen Stapf) has been used both in traditional Chinese medicine and as a nourishing food based on its unique biological effects and highly nutritional values. In the present study, we investigated the anti-tumor effect of a hot-water adlay extract in sarcoma mice model. Materials andMethods:
The hot water extract of whole adlay was orally administered to mice for one week, after which Sarcoma-180 cells (1×106) were subcutaneously implanted into the abdomen. Thereafter, the tumor growth was monitored and mouse survival was examined.Results:
Tumor weights measured at 18 days were significantly lower in mice treated with extract (100 and 300 mg/kg/day) than those in control group (p<0.01). Moreover, mice treated with extract (100 mg/kg/day) showed apparently longer survival than control group evaluated until 32 days (p<0.05).Conclusion:
These findings indicate that hot water adlay extract appears to have some anti-tumor effects in vivo insarcoma cells.
Search on Google
Index:
WPRIM (Western Pacific)
Type of study:
Prognostic study
Language:
English
Journal:
Japanese Journal of Complementary and Alternative Medicine
Year:
2020
Type:
Article
Similar
MEDLINE
...
LILACS
LIS