Progress on the role of synaptic cell adhesion molecules in stress / 生理学报
Acta Physiologica Sinica
;
(6): 220-226, 2020.
Article
in Chinese
| WPRIM
| ID: wpr-827066
ABSTRACT
Synaptic cell adhesion molecules (CAMs) are a type of membrane surface glycoproteins that mediate the structural and functional interactions between pre- and post-synaptic sites. Synaptic CAMs dynamically regulate synaptic activity and plasticity, and their expression and function are modulated by environmental factors. Synaptic CAMs are also important effector molecules of stress response, and mediate the adverse impact of stress on cognition and emotion. In this review, we will summarize the recent progress on the role of synaptic CAMs in stress, and aim to provide insight into the molecular mechanisms and drug development of stress-related disorders.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Physiology
/
Stress, Physiological
/
Stress, Psychological
/
Synapses
/
Cell Adhesion Molecules
/
Cell Adhesion
/
Neuronal Plasticity
Limits:
Humans
Language:
Chinese
Journal:
Acta Physiologica Sinica
Year:
2020
Type:
Article
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