Effect of scaling and root planing on serum C-reactive protein levels in patients with moderate to severe chronic periodontitis: a systematic review and Meta-analysis / 华西口腔医学杂志
West China Journal of Stomatology
;
(6): 385-392, 2020.
Article
in Chinese
| WPRIM
| ID: wpr-827526
ABSTRACT
OBJECTIVE@#To evaluate the effect of scaling and root planing (SRP) on serum C-reactive protein (CRP) levels in patients with moderate to severe chronic periodontitis.@*METHODS@#We searched the PubMed, Web of Science, EMBASE, Cochrane, CNKI, Wanfang, and VIP databases from the inception to July 8th, 2019. Two reviewers independently screened literature, extracted data, and evaluated the bias risk of included studies. Then, a meta-analysis was performed using RevMan 5.3 software.@*RESULTS@#A total of 13 randomized controlled clinical trials and 12 prospective clinical trials were included. Meta-analysis showed that serum CRP levels decreased at 2 and 3 months after SRP (P<0.05), and no significant difference in serum CRP levels was found at 6 months (P=0.49).@*CONCLUSIONS@#SRP can reduce serum CRP levels in systematically healthy patients with moderate to severe chronic periodontitis at 2 and 3 months after SRP.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
C-Reactive Protein
/
Prospective Studies
/
Dental Scaling
/
Root Planing
/
Chronic Periodontitis
Type of study:
Controlled clinical trial
/
Observational study
/
Systematic reviews
Limits:
Humans
Language:
Chinese
Journal:
West China Journal of Stomatology
Year:
2020
Type:
Article
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