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A new lignan glucoside from root of Paeonia lactiflora / 中国中药杂志
Article in Chinese | WPRIM | ID: wpr-828069
Responsible library: WPRO
ABSTRACT
A new lignan glucoside,(+)-fragransin A_2-4-O-β-D-glucopyranoside(1), has been isolated from the dry root of Paeonia lactiflora by column chromatography on silica gel, Sephadex LH-20, and MCI-gel resin, as well as preparative RP-HPLC. The structure of the new compound was elucidated by spectroscopic data analysis(MS, UV, IR, CD, 1 D and 2 D NMR) and chemical method. Compound 1 showed moderate inhibition against lipopolysaccharide induced nitric oxide production in RAW264.7 macrophages, with an IC_(50) value of 21.3 μmol·L~(-1).
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Plant Extracts / Chromatography, High Pressure Liquid / Lignans / Paeonia / Glucosides Language: Chinese Journal: China Journal of Chinese Materia Medica Year: 2020 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Plant Extracts / Chromatography, High Pressure Liquid / Lignans / Paeonia / Glucosides Language: Chinese Journal: China Journal of Chinese Materia Medica Year: 2020 Type: Article