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Comparative study on differences of resin-containing drugs in Dracaena from different appearance based on HS-GC-MS and chemometrics / 中国中药杂志
China Journal of Chinese Materia Medica ; (24): 3467-3474, 2020.
Article in Chinese | WPRIM | ID: wpr-828424
ABSTRACT
Resin-containing drugs in Dracaena from four different appearances were analyzed by headspace sampling-gas chromatography-mass spectrometry(HS-GC-MS) metabolomics technique and hierarchical clustering analysis(HCA) chemometrics method. This study was to analyze differential volatile components in resin-containing drugs in Dracaena from different appearance and metabolic pathways. The results of partial least squares discriminant analysis(PLS-DA) and HCA analysis indicated that there was little difference in volatile components between fiber-rich sample and hollow cork cambium sample, however, the volatile components in the two samples compared with whole body resin-containing sample and resin-secreting aggregated sample had a large metabolic difference. Twenty differential metabolites were screened by VIP and P values of PLS-DA. The content of these differential metabolites was significantly higher in whole body resin-containing sample and resin-secreting aggregated sample than in fiber-rich sample and hollow cork cambium sample. Sixteen significant metabolic pathways were obtained through enrichment analysis(P<0.05), mainly involved in terpenoids biosynthesis and phenylpropanoid metabolism. This result provided a reference for further study of resin formation mechanism of resin-containing drugs in Dracaena from different appearances. At the same time, it also provided a reference for establishing a multi-index quality evaluation system.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Resins, Plant / Cluster Analysis / Discriminant Analysis / Dracaena / Gas Chromatography-Mass Spectrometry Language: Chinese Journal: China Journal of Chinese Materia Medica Year: 2020 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Resins, Plant / Cluster Analysis / Discriminant Analysis / Dracaena / Gas Chromatography-Mass Spectrometry Language: Chinese Journal: China Journal of Chinese Materia Medica Year: 2020 Type: Article