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Effect of early continuous blood purification on the prognosis of children with septic shock: a prospective randomized controlled clinical trial / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics ; (12): 573-577, 2020.
Article in Chinese | WPRIM | ID: wpr-828704
ABSTRACT
OBJECTIVE@#To study the effect of early continuous blood purification (CBP) on the prognosis of children with septic shock.@*METHODS@#A prospective analysis was performed for the children with septic shock who did not reach the 6-hour initial recovery target and/or had a fluid overload of >10%. According to the treatment time of CBP, they were divided into an early group with 30 children and a conventional group with 28 children. The two groups were compared in terms of the start time of CBP and 28-day mortality rate, as well as the related indexes in the children who were cured.@*RESULTS@#The early group had a significantly earlier start time of CBP than the conventional group (P0.05). The children who were cured in the early group had significantly shorter correction time of lactic acid, urine volume, and fluid overload than those in the conventional group (P10%, early CBP treatment can quickly control the disease, shorten the course of disease, and accelerate immune reconstruction.
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: Prognosis / Respiration, Artificial / Shock, Septic / Prospective Studies / Lactic Acid / Fluid Therapy Type of study: Controlled clinical trial / Observational study / Prognostic study Limits: Child / Humans Language: Chinese Journal: Chinese Journal of Contemporary Pediatrics Year: 2020 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Prognosis / Respiration, Artificial / Shock, Septic / Prospective Studies / Lactic Acid / Fluid Therapy Type of study: Controlled clinical trial / Observational study / Prognostic study Limits: Child / Humans Language: Chinese Journal: Chinese Journal of Contemporary Pediatrics Year: 2020 Type: Article