Association between diabetes and nonalcoholic fatty liver disease-related hepatocellular carcinoma / 临床肝胆病杂志

ABSTRACT

Hepatocellular carcinoma(HCC) is one of the most common malignant tumors. With the development of antiviral therapy and the changes in lifestyle, the main pathogenic factor of HCC gradually changes from viral hepatitis to nonalcoholic fatty liver disease. Diabetes mellitus is a common chronic disease, and at present, there is an increasing number of patients with both nonalcoholic fatty liver disease and diabetes. Nonalcoholic fatty liver disease and diabetes share some common mechanisms, and diabetes may promote the progression of nonalcoholic fatty liver disease and increase the risk of HCC. This article reviews the association of diabetes and nonalcoholic fatty liver disease with HCC.