Role of exosomes in hepatocellular carcinoma / 临床肝胆病杂志
Journal of Clinical Hepatology
;
(12): 2333-2339, 2020.
Article
in Chinese
| WPRIM
| ID: wpr-829413
ABSTRACT
Exosomes are vesicles with a diameter of about 50-150 nm released by a variety of cells and contain miRNA, mRNA, and protein, with the potential to regulate the signal transduction pathways in receptor cells. Exosomes provide nucleic acids and proteins to coordinate cell-cell communication and microenvironment regulation. This article summarizes the latest research advances in the role of exosomes in hepatocellular carcinoma (HCC) and analyzes the effect of exosomes on the development and progression of HCC, including chemotherapy resistance, epithelial-mesenchymal transition, angiogenesis, metastasis, and immune response. The analysis shows that exosomes have a promising future in the treatment of HCC.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Clinical Hepatology
Year:
2020
Type:
Article
Similar
MEDLINE
...
LILACS
LIS