Mechanism of mitochondrial dysfunction in the development of nonalcoholic fatty liver disease / 临床肝胆病杂志
Journal of Clinical Hepatology
;
(12): 2353-2355, 2020.
Article
in Chinese
| WPRIM
| ID: wpr-829417
ABSTRACT
Nonalcoholic fatty liver disease (NAFLD) includes a series of diseases affected by various complex factors. Mitochondrial dysfunction often occurs in NAFLD and may lead to the progression of hepatitis and liver fibrosis. This article reviews the important role of mitochondrial oxidative stress, respiration, energy metabolism, quality control, and mitochondrial DNA in NAFLD and summarizes the current status of mitochondria-targeted therapy for NAFLD, hoping to provide a new direction for the research and clinical treatment of NAFLD.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Clinical Hepatology
Year:
2020
Type:
Article
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