Hepatosplenic B-cell lymphoma associated with hemophagocytic syndrome: a case report
Journal of Korean Medical Science
;
: 671-674, 1999.
Article
in English
| WPRIM
| ID: wpr-83039
ABSTRACT
While T-cell non-Hodgkin's lymphoma (NHL) associated with hemophagocytic syndrome (HPS) has been frequently observed, B-cell NHL associated with HPS has been rarely reported. We report a case of hepatosplenic B-cell lymphoma associated with HPS in a 41-year-old woman who presented with fever of unknown origin. An abdominal CT scan revealed splenomegaly with focal splenic infarction. Splenectomy and a liver wedge biopsy showed sinusoidal-pattern infiltration of medium to large tumor cells with positive reaction to a B-lymphocyte marker. Findings on bone marrow examination showed proliferation of histiocytes with avid hemophagocytosis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Splenic Neoplasms
/
Splenomegaly
/
Bone Marrow Cells
/
Antineoplastic Combined Chemotherapy Protocols
/
Biomarkers, Tumor
/
Tomography, X-Ray Computed
/
Antigens, CD
/
Histiocytosis, Non-Langerhans-Cell
/
Lymphoma, B-Cell
/
Liver Neoplasms
Limits:
Adult
/
Female
/
Humans
Language:
English
Journal:
Journal of Korean Medical Science
Year:
1999
Type:
Article
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