Molecular characteristics of meningiomas
Journal of Pathology and Translational Medicine
;
: 45-63, 2020.
Article
| WPRIM
| ID: wpr-834527
ABSTRACT
Meningioma is the most common primary intracranial tumor in adults. The grading of meningioma is based on World Health Organization criteria, which rely on histopathological features alone. This grading system is unable to conclusively predict the clinical behavior of these tumors (i.e., recurrence or prognosis in benign or atypical grades). Advances in molecular techniques over the last decade that include genomic and epigenomic data associated with meningiomas have been used to identify genetic biomarkers that can predict tumor behavior. This review summarizes the molecular characteristics of meningioma using genetic and epigenetic biomarkers. Molecular alterations that can predict meningioma behavior may be integrated into the upcoming World Health Organization grading system.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Prognostic study
Journal:
Journal of Pathology and Translational Medicine
Year:
2020
Type:
Article
Similar
MEDLINE
...
LILACS
LIS