Renal intravascular large B cell lymphoma: the first case report in Korea and a review of the literature
Journal of Pathology and Translational Medicine
;
: 426-431, 2020.
Article
| WPRIM
| ID: wpr-834570
ABSTRACT
Herein, we describe the first case of renal intravascular large B cell lymphoma in Korea occurring in a 66-year-old female. She presented with mild fever and dyspnea. On physical and laboratory evaluations, hemophagocytic lymphohistiocytosis was suspected, but the bone marrow biopsy results were unremarkable. During the work-up, massive proteinuria developed, which led to a renal biopsy. The renal architecture was relatively well-preserved, but the glomeruli were hypercellular with the infiltration of atypical, large lymphoid cells with increased nucleus-cytoplasm ratio and clumped chromatin. Similar cells were also present in the peritubular capillaries. The tumor cells exhibited membranous staining for CD20 and CD79a. After the diagnosis of intravascular large B cell lymphoma, the patient received rituximab-based chemotherapy under close follow-up.
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Index:
WPRIM (Western Pacific)
Journal:
Journal of Pathology and Translational Medicine
Year:
2020
Type:
Article
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