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Effect of warfarin discontinuation on the incidence of postoperative bleeding in tooth extraction
Journal of the Korean Association of Oral and Maxillofacial Surgeons ; : 228-234, 2020.
Article | WPRIM | ID: wpr-834706
ABSTRACT
Objectives@#The number of patients undergoing oral anticoagulant therapy for cardiovascular and cerebrovascular disease is increasing. However, the risk of bleeding after tooth extraction in patients receiving warfarin is unclear. Here, we assess the risk of bleeding after tooth extraction in patients on warfarin. @*Materials and Methods@#The study included 260 patients taking warfarin who underwent tooth extraction (694 teeth). The patients were divided into those whose teeth were extracted while they were taking warfarin, those who discontinued warfarin before extraction, and those who underwent extraction while receiving heparin bridging therapy. Bleeding complications in the two groups were compared. @*Results@#Of the 260 patients, 156 underwent extraction while taking warfarin, 70 stopped taking warfarin before extractions, and 34 received heparin bridging therapy and stopped taking either medication before extractions. Bleeding complications occurred in 9 patients (3.5%) and 9 tooth sites (1.3%). Among the 9 patients with bleeding complications, 6 underwent extraction while taking warfarin, 2 stopped warfarin before extraction, and 1 underwent extraction after receiving heparin bridging therapy. No significant difference was seen between patient groups regarding bleeding after extractions (p=0.917). @*Conclusion@#Warfarin use does not increase the risk of post-extraction bleeding and can therefore be continued during tooth extraction.
Full text: Available Index: WPRIM (Western Pacific) Type of study: Incidence study Journal: Journal of the Korean Association of Oral and Maxillofacial Surgeons Year: 2020 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Type of study: Incidence study Journal: Journal of the Korean Association of Oral and Maxillofacial Surgeons Year: 2020 Type: Article