Impact of Age on Clinicopathological Features and Survival of Patients with Noncardia Gastric Adenocarcinoma
Journal of Gastric Cancer
;
: 238-245, 2014.
Article
in English
| WPRIM
| ID: wpr-83548
ABSTRACT
PURPOSE:
Gastric cancer often occurs in the elderly but is uncommon in young individuals. Whether young patients have different clinical behaviors and outcomes from those of older patients remain unclear. MATERIALS ANDMETHODS:
We identified 1,366 cases of newly diagnosed noncardia gastric adenocarcinoma from the Kaiser Permanente Northern California Cancer Registry between 2000 and 2010. We then compared the clinicopathological features and survival among the different age groups.RESULTS:
The male female ratio differed significantly between the younger and older patient groups (0.84 in age 60 years, P or =70 years, P or =70 years vs. 15% patients or =70 years; P or =70 years vs. 30% in patients or =70 years; P=0.016). Survival rates at 1, 2, and 5 years gradually declined with increasing age (overall P=0.0002).CONCLUSIONS:
Young patients with gastric cancer had more aggressive disease but higher overall survival rates than older patients. Younger Hispanic patients and older Caucasian patients were more likely to be diagnosed with gastric cancer. These differences may be due to biological predisposition and/or environmental exposure.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Stomach Neoplasms
/
Adenocarcinoma
/
Ethnicity
/
Hispanic or Latino
/
California
/
Survival Rate
/
Outcome Assessment, Health Care
/
Environmental Exposure
Limits:
Aged
/
Female
/
Humans
/
Male
Country/Region as subject:
North America
Language:
English
Journal:
Journal of Gastric Cancer
Year:
2014
Type:
Article
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