Survival Factors among Medical Intensive Care Unit Patients with Carbapenemas-ProducingEnterobacteriaceae
Journal of Korean Biological Nursing Science
;
: 249-259, 2020.
Article
in English
| WPRIM
| ID: wpr-835922
ABSTRACT
Purpose@#Carbapenemase-producing Enterobacteriaceae (CPE) are associated with considerable mortality. This study was aimed to identify survival factors among medical care unit patients with CPE. @*Methods@#We conducted a retrospective cohort; data were collected from September 2017 to June 2019 through electronic medical records. The data collected were general characteristics, disease-related characteristics, severity-related characteristics, and treatment-related characteristics. Data were analyzed based on frequency, mean, standard deviation, Chi-square test, Fisher’s exact test, t-test, Pearson’s correlation coefficient, and Cox proportional hazard model using SPSS/WIN 21.0 program. @*Results@#Seventy-seven patients were included (59 survivors and 18 deceased) in the study. Univariate analysis identified factors for survival associated with acquired CPE as age (t= -1.56, p= .037), simplified acute physiology 3 (SAPS3) score of admission date (t= -2.85, p= .006), Glasgow coma scale (GCS) of CPE acquisition date (t= 2.38, p= .020), artery catheter at CPE acquisition date (χ2 = 4.58, p= .032), vasoconstrictor agents use at CPE acquisition date (χ2 = 6.81, p= .009), platelet at CPE acquisition date (t= 2.27, p= .025), lymphocyte at CPE acquisition date (t= 2.01, p= .048), calcium at CPE acquisition date (t= 2.68, p= .009), albumin at CPE acquisition date (t= 2.29,p= .025), and creatinine at CPE acquisition date (t= 2.24, p= .028). Multivariate Cox proportional hazard model showed that GCS at CPE acquisition date (HR= 1.14, 95% CI= 1.05-1.22), lymphocyte at CPE acquisition date (HR= 1.05, 95% CI= 1.00-1.10), and creatinine at CPE acquisition date (HR= 1.25, 95% CI= 1.04-1.49) were independent survival factors among medical intensive care unit patients with CPE. @*Conclusion@#Based on the study results, it is necessary to develop nursing interventions that can aid in the management of patients with CPE and identify their effects.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Prognostic study
Language:
English
Journal:
Journal of Korean Biological Nursing Science
Year:
2020
Type:
Article
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