Clinical presentations and outcome of the urinary bladder sarcomas in adult: review and discussion of surgical treatment

ABSTRACT

Background: Urinary bladder sarcomas are rare in adults, accounting for 0.38-0.64% of bladder tumors. The most recognized treatment for malignant tumors is chemotherapy followed by radiotherapy, but there have been no large scale study to provide a definitive regimen for this condition. Objectives: To determine the outcome of patients with urinary bladder sarcomas. Subjects and method: Between January 2002 and December 2006, 6 patients diagnosed with urinary bladder sarcomas were examined at the Viet Duc Hospital. We retrospectively reviewed the records of these patients for information on clinical features, treatment and outcomes. Results: The mean age of patients was 39.6 years; male/female ratio was 3/1; 66% was leiomyosarcomas, 16.7% was rhabdomyosarcomas, 16.7% was myxosarcomas (n=6). Among these malignant tumors, 3/5 patients were in the advanced stage. Conclusion: Bladder sarcomas were rare in adults. Leiomyosarcomas were more common than rhabdomyosarcomas and had worst outcomes if it is in an advanced stage.