Comparison of Two Multi-Step Programs for Early Detection of Amnestic Mild Cognitive Impairment in the Community

ABSTRACT

Objective@#Amnestic mild cognitive impairment (aMCI) has high conversion risk to dementia. However, it is not easy to detect aMCI patient early in the community. This study aimed to compare two-step and three-step program for early detection of aMCI in the community. @*Methods@#Overall 5,155 persons participated who were already registered with Korean version of Mini-Mental Status Examination for Dementia Screening (MMSE-DS) evaluation. It was conducted across 5 all districts of Gwangju, Republic of Korea from Jan 1, 2018 to March 31, 2018. As first step, we screened them applying inclusion criteria of age, sex, education adjusted norm based MMSE Z score between -1.5 and 0. Second evaluations which are not included in two-step program, were done by telephone interviews with asking subjective memory complaints and 5 word lists recall tests. And third assessments of neuropsychological tests and clinical diagnosis with visit were performed. Author compared two-step program and three-step program for aMCI diagnostic rate. @*Results@#Two multi-step programs had no significant difference on aMCI diagnostic rate (p=0.81). @*Conclusion@#Our study suggests that two multi-step programs are similar for early detection of aMCI in the community.