Recent Update of Endoscopic Radiofrequency Ablation for Pancreatobiliary Disease / 대한췌담도학회지

ABSTRACT

Despite rapid changes in diagnosis and treatments, pancreatobiliary malignancy has increased in recent years and still has a poor prognosis. Although mainstay of treatment depends on the type of malignancy and the stage, only surgery can be expected to cure, but difficult to apply in all patients. Because most of them are diagnosed at locally advanced or metastatic at presentation, local treatment such radiofrequency ablation (RFA) and photodynamic therapy is emerged as promising therapeutic modality which can directly ablate the malignant tissues in addition to systemic anti-cancer treatment. To date, some studies could support beneficial effects of them, however it has not been confirmed whether RFA is related to favorable treatment outcomes in patient with pancreatobiliary malignancies. Therefore, this review focuses on clinical application and appropriate use of endoscopic retrograde cholangiopancreatography guided intraductal RFA along with their benefits and complications.