Duodenal Mucosa-associated Lymphoid Tissue Lymphoma Treated with Chemotherapy

ABSTRACT

Mucosa-associated lymphoid tissue (MALT) lymphomas most commonly occur in the stomach and rarely in the duodenum. Gastric MALT lymphoma is usually associated with Helicobacter pylori (H. pylori) infection that may be cured by eradication. However, duodenal MALT lymphoma is not associated with H. pylori infection. Moreover, the pathophysiology and treatment methods for duodenal MALT lymphoma have not yet been established because the disease is rare. Here, we report a case of duodenal MALT lymphoma. A 58-year-old man was treated for a refractory duodenal ulcer. Based on repeated biopsy, a diagnosis of MALT lymphoma was made. The patient achieved complete remission after chemotherapy and was followed up without recurrence for three years.