Hypernatremia increases the incidence of late delirium after cardiac surgery / 中国胸心血管外科临床杂志
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
;
(12): 1320-1325, 2020.
Article
in Chinese
| WPRIM
| ID: wpr-837555
ABSTRACT
@#Objective To analyze whether hypernatremia within 48 hours after cardiac surgery will increase the incidence of delirium which developed 48 hours later after surgery (late-onset delirium). Methods We conducted a retrospective analysis of 3 365 patients, including 1 918 males and 1 447 females, aged 18-94 ( 60.53±11.50) years, who were admitted to the Department of Cardiothoracic and Vascular Surgery of Nanjing First Hospital and underwent cardiac surgery from May 2016 to May 2019. Results A total of 155 patients developed late-onset delirium, accounting for 4.61%. The incidence of late-onset delirium in patients with hypernatremia was 9.77%, the incidence of late onset delirium in patients without hypernatremia was 3.45%, and the difference was statistically different (P<0.001). The odds ratio (OR) of hypernatremia was 3.028 (95% confidence interval 2.155-4.224, P<0.001). The OR adjusted for other risk factors including elderly patients, previous history of cerebrovascular disease, operation time, cardiopulmonary bypass time, lactate, hemoglobin≥100 g/L, prolonged mechanical ventilation, left ventricular systolic function, use of epinephrine, use of norepinephrine was 1.524 (95% confidence interval 1.031-2.231, P=0.032). Conclusion Hypernatremia within 48 hours after cardiac surgery may increase the risk of delirium in later stages.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Incidence study
/
Risk factors
Language:
Chinese
Journal:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
Year:
2020
Type:
Article
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