Insulin nanoparticles with high oral bioavailability: Research progress / 第二军医大学学报
Academic Journal of Second Military Medical University
;
(12): 1027-1030, 2020.
Article
in Chinese
| WPRIM
| ID: wpr-837772
ABSTRACT
Diabetes is a chronic metabolic disease characterized by changes in the dynamic balance of blood glucose levels. Subcutaneous injection of insulin is a first-line treatment for diabetes. However, patient compliance is poor due to pain, discomfort, and local infection. Oral administration is convenient and safe, but the existing oral insulin preparations still need to be optimized due to gastrointestinal instability and poor bioavailability. The rapid development of nanopreparation technology provides a solid foundation for improving the bioavailability of oral insulin preparations and achieving the effective oral delivery of insulin. This paper reviews the research progress in insulin nanoparticles with high oral bioavailability in recent years.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Academic Journal of Second Military Medical University
Year:
2020
Type:
Article
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