Recent vaccine technology in industrial animals
Clinical and Experimental Vaccine Research
;
: 12-18, 2016.
Article
in English
| WPRIM
| ID: wpr-8378
ABSTRACT
Various new technologies have been applied for developing vaccines against various animal diseases. Virus-like particle (VLP) vaccine technology was used for manufacturing the porcine circovirus type 2 and RNA particle vaccines based on an alphavirus vector for porcine epidemic diarrhea (PED). Although VLP is classified as a killed-virus vaccine, because its structure is similar to the original virus, it can induce long-term and cell-mediated immunity. The RNA particle vaccine used a Venezuela equine encephalitis (VEE) virus gene as a vector. The VEE virus partial gene can be substituted with the PED virus spike gene. Recombinant vaccines can be produced by substitution of the target gene in the VEE vector. Both of these new vaccine technologies made it possible to control the infectious disease efficiently in a relatively short time.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Venezuela
/
RNA
/
Vaccines
/
Vaccines, Synthetic
/
Communicable Diseases
/
Circovirus
/
Alphavirus
/
Diarrhea
/
Encephalitis Virus, Venezuelan Equine
/
Encephalomyelitis, Equine
Limits:
Animals
Country/Region as subject:
South America
/
Venezuela
Language:
English
Journal:
Clinical and Experimental Vaccine Research
Year:
2016
Type:
Article
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