Relationship between blood pressure level and urinary micro-albumin and other influencing factors / 第二军医大学学报

ABSTRACT

Objective To explore the relationship between blood pressure level and urinary micro-albumin, kidney damage and metabolic indicators, so as to provide scientific evidence for the prevention and treatment of hypertension. Methods Using stratified multi-stage random sampling method, we selected local residents (15 years old) in Tongnan area of Chongqing for questionnaire survey, physical examination, and the detection of blood and urine samples to obtain blood glucose, blood lipids, urinary micro-albumin, and other clinical data. The data were statistically analyzed by SPSS 20.0 software. Results The proportions of patients with microalbuminuria (urinary micro-albumin level≥20 mg/L) in the normal blood pressure group, the prehypertension group, and the hypertension group were 21.40% (61/285), 27.36% (110/402) and 48.06% (149/310), respectively, and there were significant differences between the three groups (P0.05). The proportion of patients with microalbuminuria in the hypertension patients was significantly increased with the increase of blood pressure (P0.05). Multiple linear regression analysis showed that systolic blood pressure was significantly increased with the increase of triglyceride and low-density lipoprotein cholesterol levels (P0.05), and diastolic blood pressure was significantly increased with the increase of triglyceride level (P0.05). Binary logistic regression analysis showed that urinary micro-albumin, high-density lipoprotein cholesterol, age and waist circumference were the influencing factors of hypertension (P0.05). Conclusion Urinary micro-albumin level is closely related to blood pressure level, and can be used as an important indicator for the diagnosis of early renal damage diagnosis. Urinary micro-albumin, high-density lipoprotein cholesterol, age and waist circumference are independently associated with hypertension.