Research progress on role of macrophage in fracture healing / 第二军医大学学报
Academic Journal of Second Military Medical University
;
(12): 1556-1561, 2017.
Article
in Chinese
| WPRIM
| ID: wpr-838526
ABSTRACT
Inflammatory reaction plays an important role in hematoma formation, tissue debris removal and fibrous tissue formation during the first stage of fracture healing. M1 and M2 macrophages participate in the process of fracture healing through pro-inflammatory and anti-inflammatory effects, respectively. Tumor necrosis factor α, interleukin and other cytokines secreted by macrophages can regulate the activities of osteoblasts and osteoclasts. Bone tissue bioengineering studies found that functional tissue engineering can promote angiogenesis and fracture healing by regulating inflammatory reaction. Therefore, exploring the role of macrophages in the process of fracture healing may provide new insights for promoting fracture healing.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Academic Journal of Second Military Medical University
Year:
2017
Type:
Article
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