Relationship between P2X7 receptor and bone metabolism: Recent progress / 第二军医大学学报

ABSTRACT

P2X7 receptor, an ATP-gated ion channel, is widely found in various tissues and possesses multiple physiological functions. Recent reports have implicated expression of P2X7 receptor in both osteoblasts and osteoclasts, participating in both bone formation and resorption. This paper reviews the recent progresses on the influence of P2X7 receptor and its related pathways on bone metabolism.