Primary pulmonary plasmacytoma: A case report and review of the literature / 第二军医大学学报

ABSTRACT

Objective To describe the characteristics of primary pulmonary plasmacytoma. Methods One patient with primary pulmonary plasmacytoma was described and relevant literatures were reviewed. Results Primary pulmonary plasmacotyma is a very rare form of extramedullary plasmacytoma.Patients with this disease usually have little symptoms. Primary pulmonary plasmacytoma often presents as solitary or multiple nodular mass lesions, but these lesions lack specific radiographic features and are easily lead to misdiagnosis. The diagnosis of primary pulmonary plasmacotyma is based on the histological confirmation of plasma cell infiltration in lung lesions. Additionally, it requires normal bone marrow, normal skeletal survey, no related organ or tissue impairment, and no M protein in serum and/or urine. Most cases of solitary pulmonary plasmacytoma can be treated with surgical resection and/or irradiation, and combination chemotherapy is effective for cases of diffuse pulmonary infiltration. Conculsion Biopsy and pathologic diagnosis is very important to patients who present as solitary or multiple nodular mass lesions to avoid misdiagnosis and mistreatment.