Antioxidant defense of peroxiredoxin 6 in lung: Recent progress / 第二军医大学学报
Academic Journal of Second Military Medical University
;
(12): 1121-1125, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-839225
ABSTRACT
Alveolar epithelial apoptosis and injury induced by oxidative stress in pulmonary diseases have drawn great attention from researchers. Peroxiredoxin 6 (Prdx6), endowed with the activities of both glutathione (GSH) peroxidase and phospholipase A2(PLA2), can effectively fight against oxidative stress and alleviate oxidative stress-induced lung injury, and therefore plays an important role in pulmonary diseases. This review focuses on the structure, function, distribution and expression regulation of Prdx6, and summarizes the role of Prdx6 in pulmonary antioxidant defense and its regulatory mechanism based on experimental studies.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Academic Journal of Second Military Medical University
Year:
2014
Type:
Article
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