Muco-Cutaneous Lymph node Syndrome: Clinical observation of twentycases

ABSTRACT

Authors experienced the cases like to Muco-Cutaneous Lymph node Syndrome (MCLS) admitted to the department of Pediatrics, St. Benedict Hospital from Jan. 1978 to Dec. 1979. Here Authors presented the clinical datas of twenty cases simulating this syndrome as reported by Kawasski. 1. The peak age group was from 1 to 2 years of age and the youngest case was 3 months old infant. Most of them (95%) was under 3 yesrs old. The ratio of male and female was 13 to 7. The seasonal incidence was higher in May to June and November to February. The annual incidence of 1979 was more than 2 times as that of 1978. 2. The clinical symptoms on admission were as follow fever (100%), cough (70%), diarrhea (65%), vomiting (45%), irritability (40%), So, on admission, Authors had used to overlook as respiratory disease or acute gastroenteritis. 3. The 70% of them showed at least 5 items of the principal symptoms of MCLS. At acute phase, 14 cases (70%) also showed the erythematous desquamation of anogenital region, and 2 cases (10%) showed a transitory hydrocele. The appearance of rashes was observed in 10 cases (50%), and 7 cases of the remainder showed the desquamation of digits during convalescent phase. 7 of 15 cases (46.7%) showed only the desquamation of fingertips. 4. 8 cases (40%) had sinus tachycardia, and I case had gallop rhythm. Most of them showed normal EKG, and 4 cases (20%) showed low voltage of limb leads. 5. In the laboratory findings, most of them had leucocytosis, elevated ESR, positive CRP, normal ASO, and 5 cases (25%) had slight increase of serum transminase. Hepatomegaly was observed in 7 cases (35%). 6. In spite of the intensive treatment, fever was continued for about 5 days in 5 cases (25%).