Expression and significance of YKL-40 and VEGF in condyloma acuminatum tissues / 第二军医大学学报

ABSTRACT

Objective To explore the expression of YKL-40 and vascular endothelial cell growth factor (VEGF) in condyloma acuminatum (CA tissues and the related significance. Methods The expressions of YKL-40 and VEGF were analyzed by immunocytochemical staining with streptavidin-peroxidase (SP) in 33 CA tissues and 10 foreskin tissues of normal person. Results The expression intensities of YKL-40 and VEGF varied largely from positive (#) to strongly positive ($) in CA tissues compared with negative ( - ) and positive ( + ) in normal foreskin tissues. The expressions of YKL-40 and VEGF proteins in CA tissues were significantly different from those in the normal human controls(P0. 05). No correlation was found between the expression of YKL-40 and VEGF proteins in CA tissues (r = 0. 27, P