Biotransformation of 4 ent-labdane diterpenoid lactones of Andrographis paniculata: Recent progress / 第二军医大学学报
Academic Journal of Second Military Medical University
;
(12): 1130-1136, 2013.
Article
in Chinese
| WPRIM
| ID: wpr-839488
ABSTRACT
Ent-labdane diterpenoid lactones, the principal constituents of Andrographis paniculata, have a wide range of pharmacological effects, such as antibacterial, anti-viral, anti-inflammatory, antipyretic, andanti-cancer effect, etc. In this review the biotransformations of four principal ent-labdane diterpenoid lactones of A. paniculata are discussed from the following aspects substrates and types of reaction, transformation systems, and structure activity relationships. Moreover, the currently-existing problems and the prospects are also described to provide reference for further studying the biotransformation of ent-labdane diterpenoid lactones of A. paniculata.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Academic Journal of Second Military Medical University
Year:
2013
Type:
Article
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