Hormone Therapy in Postmenopausal Women
Journal of the Korean Medical Association
;
: 377-384, 2005.
Article
in Korean
| WPRIM
| ID: wpr-84017
ABSTRACT
Until the results of Women's Health Initiative (WHI) was released in July 2002, hormone replacement after menopause had been thought to be the most effective way to manage menopause-related symptoms and to prevent longterm related diseases including osteoporosis, cardiovascular disease, and Alzheimer's disease. A significant increase in breast cancer incidence (by 26%) brought the early termination of the WHI study. After an assessment of the overall risk-benefit ratio, the WHI investigators failed to demonstrate beneficial effects of the combined hormone therapy. This article reviews the results of several large randomized controlled studies and discusses the risks and benefits of hormone therapy.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Osteoporosis
/
Research Personnel
/
Breast Neoplasms
/
Menopause
/
Cardiovascular Diseases
/
Incidence
/
Women's Health
/
Risk Assessment
/
Alzheimer Disease
Type of study:
Controlled clinical trial
/
Etiology study
/
Incidence study
/
Prognostic study
/
Risk factors
Limits:
Female
/
Humans
Language:
Korean
Journal:
Journal of the Korean Medical Association
Year:
2005
Type:
Article
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