Multi-mode ultrasound analysis of male breast cancer / 第二军医大学学报

ABSTRACT

Objective: To analyze the multi-mode ultrasound manifestation of male breast cancer, and to discuss its value in clinical diagnosis and differential diagnosis. Methods: The clinical data of 15 male patients with pathologically-confirmed breast cancer were retrospectively reviewed. All the patients were examined by multi-mode ultrasound (including 2D, 3D, color Doppler flow imaging [CDFI], and intravenous contrast-enhanced ultrasound [CEUS]). The ultrasonic characteristics of the 8 patients were compared with those of 7 patients with hyperplasia. The diagnostic values of the ultrasonic characteristics were summarized. Results: (1) 2D sonogram 6 of 7 cases with ultrasonically diffused masses, which were all initially interpreted as hyperplasia on ultrasound, were confirmed pathologically, with an accurate rate of 86%. All the 8 patients had unilateral focal masses (ipsilateral in 3 of 8). They were all diagnosed as having breast cancer by ultrasound, with hypoechoes and irregular shape. Three of them had micro-calcification. All the 8 patients were confirmed to have breast cancer pathologically, with the accurate rate of ultrasound being 100%. (2) CDFI and CEUS hyperplasia patients had weak blood flow signal and breast cancer patients all had rich blood flow signal. High frequency CEUS showed that only 3 breast cancer patients had marked micro-vascular enhancement, while low-frequency CEUS showed prominent enhancement in all cancer cases. (3) 3D reconstruction coronary display of 2 focal masses showed "convergent sign". Conclusion: Multi-mode ultrasound imaging can provide comprehensive information of male patients with breast disorders; it may facilitate the early detection, early diagnosis and early treatment for male breast cancer.