Cubosomes as drug delivery system: Recent advance / 第二军医大学学报
Academic Journal of Second Military Medical University
;
(12): 834-839, 2010.
Article
in Chinese
| WPRIM
| ID: wpr-840542
ABSTRACT
Cubosomes are self-assembled nanostructured particles formed by aqueous lipid and surfactant systems. Cubosomes are thermodynamically stable; they have a structure like "honeycombed" with bicontinuous domains of water and lipid in which surfactant assembles into bilayers and twisted into a three dimension, periodic, and minimal surface, forming a tightly packed structure. The properties of cubosomes, such as its unique bicontinuous cubic phase liquid crystals, its ability to solubilize hydrophobic, hydrophilic, and amphiphilic molecules at the same time, its biodegradability by simple enzyme action, its strong bioadhesion ability, and its simple preparation, make them a promising vehicle for drug delivery. Based on recent reports, this review introduces the structure, preparation, exosyndrome and drug delivery potential of cubosomes.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Academic Journal of Second Military Medical University
Year:
2010
Type:
Article
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