Phenolic glycosides and lignans components in Curculigo orchioides Gaertn / 第二军医大学学报

ABSTRACT

Objective: To isolate and identify phenolic glycosides and lignans from the rhizomes of Curculigo orchioides Gaertn. Methods: Phenolic glycosides and lignans were isolated by silica gel, Sephadex LH-20 chromatography and semi-preparative HPLC methods. The structures of the isolated compounds were identified by physiochemical and spectral analysis/ Results: Five phenolic glycosides,one lignan and one sitosterol were isolated and identified from Curculigo orchioides Gaertn, namely, 2,6-dimethoxy benzolic acid(1), curculigoside A(2), curculigoside B(3), curculigine A(4), 4-dichlorine-5-hydroxyl-3-methylphenol-1-O-β- D-glucopyranosyl-(1→-6)-β-3-D-gluco-pyranosede(5), 3,3′,5,5′-tetramethoxy-7,9′7′,9 -diepoxylignan -4, 4′-di-O-β-D-glucopyranoside(6),and β-sitosterol(7). Conclusion: Seven compounds have been isolated from Curculigo orchioides Gaertn; compound 5 is a new chlorine-containing phenol, and is named as curculigine D.