A prospective study on primary prevention of major vascular lesions of type 2 diabetes mellitus patients in Han population in Northeast China / 吉林大学学报(医学版)
Journal of Jilin University(Medicine Edition)
;
(6): 1243-1248, 2018.
Article
in Chinese
| WPRIM
| ID: wpr-841820
ABSTRACT
Objective:
To explore the changes of incidence of major vascular lesions after intensive intervention of multiple controllable risk factors in the type 2 diabetes mellitus (T2DM) patients in Han population in Northeast China, and to establish an effective, standardized and cost-effective intervention scheme for the primary prevention of major vascular lesions of the T2DM patients.Methods:
A total of 300 T2DM patients newly diagnosed or diagnosed in one year without major vascular lesions were randomly divided into conventional treatment group (n= 150) and intensive intervention group (n=150). The clinical study method of parallel control was used to intervene in the some controllable risk factors for 2 years to varying degrees. The body mass index (BMD, waist/hip ratio (WHR), systolic blood pressure (SBP), diastolic blood pressure (DBP), fasting blood glucose (FPG), 2 h postprandial blood glucose (2 h PBG), glycosylated hemoglobin (HbAlc), serum total cholesterol (TC), triglyceride (TG), low density lipoprotein cholesterol (LDL-c), high density lipoprotein (HDL-c), intima media thickness (IMT) and incidence of majoy vascular lesions of atherosclerosis (AS) of the patients in two groups were measured, and the medical expenses of the patients were analyzed statistically.Results:
After 2-year-follow-up, the DBP, FBG, 2 h PBG, HbAlc, TG, TC and HDL-c of the patients in conventional treatment group were significantly lower than those before treatment (PConclusion:
Intensive intervention of multivessel risk factors of is an effective way to prevent and treat the major vasular lesions of the T2DM patients.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Observational study
/
Risk factors
Language:
Chinese
Journal:
Journal of Jilin University(Medicine Edition)
Year:
2018
Type:
Article
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