New coumarin glucopyranosides from roots of Angelica dahurica / 中草药·英文版

ABSTRACT

Objective: To investigate the chemical constituents from the roots of Angelica dahurica. Methods: The chemical constituents were isolated and purified by AB-8 macroporous adsorption resin and Sephadex LH-20 column as well as semi-preparative reversed phase HPLC. The chemical structures were identified by spectral data. Results: Ten compounds were isolated and identified as xanthoarnol-3′-O-β-D-glucopyranoside (1), angedahuricoside A (2), angedahuricoside B (3), isofraxidin-7-O-β-D-glucopyranoside (4), fraxidin-8-O-β-D-glucopyranoside (5), (-)-marmesinin (6), (2′S,3′R)-3′-hydroxymarmesinin (7), hyuganoside V (8), daucosterol (9), and sucrose (10). Conclusion: Compounds 1–3 are new ones and compounds 4–6 and 8 are obtained from title plant for the first time.