Global methylation status of sperm DNA in carriers of chromosome structural aberrations / 亚洲男科学杂志(英文版)

ABSTRACT

Male infertility might be clearly associated with aberrant DNA methylation patterns in human spermatozoa. An association between oxidative stress and the global methylation status of the sperm genome has also been suggested. The aim of the present study was to determine whether the global sperm DNA methylation status was affected in the spermatozoa of carriers of chromosome structural aberrations.