Prognostic significance of age in curatively resected gastric cancer / 대한내과학회지
Korean Journal of Medicine
;
: 299-307, 2005.
Article
in Korean
| WPRIM
| ID: wpr-84374
ABSTRACT
BACKGROUND:
The purpose of this study was to clarify whether the patients' age is an independent prognostic factor in curatively resected gastric adenocarcinoma.METHODS:
Clinicopathologic information was reviewed for consecutive patients undergoing curative gastrectomy for gastric cancer during 6-year period (Jan. 1996-Dec. 2001) at the Keimyung University School of Medicine at Daegu. Overall survival was examined by the Kaplan-Meier method, and multivariate analysis by Cox proportional hazards was used to identify whether age had independent prognostic significance for survival.RESULTS:
The patients were divided into two groups 838 patients (72.4%) with age of less than 65 years old, and 320 patients (27.6%) with age more than 65 years old. In these two groups, there were statistically differences in WHO classification, Lauren classification, vascular invasion, T stage, total stage, operational morbidity and mortality, and overall survival rate. The 5-year overall survival rate of age less than 65 years old was 87.8%, and 83.0% of age more than 65 years old (p=0.019). Multivariate Cox regression analysis revealed that age was an independent prognostic factor to predict overall survival in curatively resected gastric cancer (p=0.038). However, after excluding cases who died within 1 month after gastric resection, overall survival rate was significantly different between two groups (p=0.050), but Cox regression analysis showed that age was not an independent prognostic factor (p=0.054).CONCLUSION:
The age is not an independent prognostic factor in curatively resected gastric cancer patients, and survival differences are due to an increased operative mortality in elderly patients.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Prognosis
/
Stomach Neoplasms
/
Adenocarcinoma
/
Multivariate Analysis
/
Survival Rate
/
Mortality
/
Classification
/
Gastrectomy
Type of study:
Prognostic study
Limits:
Aged
/
Humans
Language:
Korean
Journal:
Korean Journal of Medicine
Year:
2005
Type:
Article
Similar
MEDLINE
...
LILACS
LIS