Intensity-modulated radiation therapy for locally inoperable adenoid cystic carcinoma of the trachea and the bronchus / 西安交通大学学报(医学版)

ABSTRACT

Objective: To analyze the clinical features and treatment of tracheal adenoid cystic carcinoma (TACC) so as to explore the therapeutic value of intensity-modulated radiotherapy in treating locally advanced inoperable tracheal bronchial adenoid cystic carcinoma. Methods: A patient with locally inoperable TACC was retrospectively reported with intensity-modulated radiotherapy, and the efficacy of interventional radiotherapy for locally inoperable TACC was analyzed. Results: After multi-course chemotherapy and radical radiotherapy, the patient was given intensity-modulated radiotherapy of DT46 GY/23F in the trachea and the bronchus and in the drainage area of mediastinal lymph node. Then the tumor area of the constricted trachea and the right main bronchus was given the radiotherapy up to DT60 GY/30F. The symptoms of shortness of breath and cough disappeared, and the tracheal and bronchial lesions were completely relieved. By combining with existing reports, single radiotherapy in locally advanced inoperable TACC can achieve survival of over one year and as long as 5 to 10 years in some patients. Results: Intensity-modulated radiotherapy has a positive significance in the treatment of locally advanced inoperable TACC.