Correlation between neck circumference and stable coronary artery disease: A cross-sectional study / 西安交通大学学报(医学版)

ABSTRACT

Objective To investigate the relationship between neck circumference and stable coronary artery disease (SCAD). Methods A total of 1638 patients who had undergone coronary angiography in our hospital from June 2016 to June 2018 were enrolled into this study and analyzed retrospectively. Of them, 756 patients were diagnosed with SCAD and 882 patients were diagnosed with non-CAD. We measured the patients' body fat indexes such as neck circumference and recorded their clinical data and biochemical examination results. The correlation between neck circumference and SCAD in male and female patients was compared by gender. Logistic regression was used to analyze the independent association between the four different neck circumference groups and the occurrence of SCAD. Results Individuals with greater length of neck circumference tended to have a significantly higher prevalence of SCAD in the males (P<0.001), but no significant difference in the female patients. Univariate logistic regression analysis suggested that the risk of SCAD increased gradually with the increase of neck circumference in the males. After adjustment by the factors, multivariate logistic regression analysis indicated that Q2 (OR=1.870, 95% CI 1.200-2.915, P=0.006), Q3 (OR=1.978, 95% CI 1.246-3.140, P=0.004) and Q4 (OR=2.299, 95% CI 1.439-3.674, P<0.001) were associated with the occurrence of SCAD in the males. However, no significant difference was found between the different neck circumference and the occurrence of SCAD in the females. Conclusion The risk of SCAD increased gradually in men with an increased neck circumference. Men with neck circumference above 41.50 cm had the highest prevalence of SCAD. In women, neck circumference was not associated with the prevalence of SCAD.